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Many drugs can interact with ticagrelor. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any you start or stop using, especially:

  • imatinib;

  • lovastatin (Advicor, Altoprev, Mevacor) or simvastatin (Zocor, Simcor, Vytorin, Juvisync);

  • nefazodone;

  • St. John's wort;

  • an antibiotic--clarithromycin, telithromycin;

  • antifungal medicine--itraconazole, ketoconazole, posaconazole, voriconazole;

  • heart or blood pressure medicine--digoxin, nicardipine, quinidine;

  • antiviral medicine to treat hepatitis or HIV/AIDS--atazanavir, boceprevir, cobicistat, delavirdine, efavirenz, fosamprenavir, indinavir, nelfinavir, ritonavir, saquinavir, telaprevir;

  • seizure medicine--carbamazepine, phenytoin; or

  • tuberculosis medicine--isoniazid, rifampin.

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